Basic Information
VIS ID
TVIS10014759
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1818
Orient
+
Integrated sequence
TTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
22353678/22342357 (Hg38)
End
22353678/22342357 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1225/Upstream/836222; hsa-mir-11401/Downstream/1860759;
Nearest TSS
ENST00000527434/Upstream/10922; ENST00000566764/Downstream/7416;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/16102, chr16-CpG: 133/Downstream/31399
Nearby gene
POLR3E(-7254) ; CDR2(+3579) ;
Upstream sequence
aaaacacaacaggactacctcaaacaaaagcttctgtacagcaaaggaaacaacatgaaaaggcagcctacgcactgggagaaaatacttgcaaactata
Downstream sequence
tatctaataaggggttactaaccaaaatatatagggaactcaatagcattcaaatgaataacctgattttaaaatgggcaaagcatctgaatagacattt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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