PTPRZ1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014761
Fusion event
HBV-PTPRZ1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AB033550.1
Start
1761
Orient
+
Integrated sequence
ACTCTTGGACTCTCATCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAA| |AGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACT
Host Sequence
Chromosome
chr7
Cytoband
q31.32
Reference genome
GRCh37/hg19
Start
121520007/121879953 (Hg38)
End
121520007/121879953 (Hg38)
Orient
+
Location type
Intronic
Target gene
PTPRZ1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-181a-5p ; hsa-mir-200c-3p
Nearest miRNA
hsa-mir-10525/Upstream/4859634; hsa-mir-10399/Downstream/5178135;
Nearest TSS
ENST00000635602/Upstream/6592; ENST00000483028/Downstream/131255;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/6225, chr7-CpG: 61/Downstream/263939
Upstream sequence
ATGTCCAAACTTTGTGTATTTCAGTTTTAAAAAGAATCTGCAGAATATAATTCTTGGCAATCAGCCAGTAAGTGCCTACACACTTTTCTAAGCACAATTA
Downstream sequence
CTTAAGTTTGCTCAGCACCTTGATGAAAAGTTTGATAGGGAAGAGATTAATGCTATTTGAAACCATTAGTTAAAAATATTTTTACTGTGTTAATATCATT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate