Basic Information
VIS ID
TVIS10014773
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
816
Orient
+
Integrated sequence
CCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATTACCAATTTTCTTTTG| |TCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTACCACAGG
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
104473938/103821588 (Hg38)
End
104473938/103821588 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1297/Upstream/1775584; hsa-mir-1267/Downstream/3709583;
Nearest TSS
ENST00000623511/Upstream/396388; ENST00000640578/Downstream/1644279;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/975175, chr13-CpG: 29/Downstream/2671472
Upstream sequence
AATGAATGCATGATTTACACGAGACATGAAATTATATTTCCAGTTATAGCTCTACATAAAGATTTCTAATGACAAGAAAATGAGGAACATGAAACTTTCA
Downstream sequence
AAACAATATAGCTCATCCGTGAGCTCCCTTATCCAATACTCTTAAAATTTGTATTTTTACCCAAAAATACATTTATGATTCCATAATTTTTATTCATTAT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate