Basic Information
VIS ID
TVIS10014778
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1760
Orient
+
Integrated sequence
GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA| |AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTAC
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
80934672/80468987 (Hg38)
End
80934672/80468987 (Hg38)
Orient
-
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/3408785; hsa-mir-11399/Downstream/4664807;
Nearest TSS
ENST00000473358/Upstream/94366; ENST00000418041/Downstream/66768;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/137786, chr1-CpG: 281/Downstream/1331326
Upstream sequence
cataattgattttttatacagtagaaggtaATGAGTAAATCAATTTGTTGAAAATTTTAGATGGTAAATGAATAATTACAataaaatgtctctcttcata
Downstream sequence
tctagtaatgttgcattgaagtctgctttgactgatattaatgtaattacatcagatttattttgtcagttatttttatgacatatctttctatcgtttt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate