Basic Information
VIS ID
TVIS10014781
Fusion event
HBV-LOC100422352 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1801
Orient
+
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |TTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
30643805/30490872 (Hg38)
End
30643805/30490872 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC100422352
Nearest miRNA
hsa-mir-1244-3/Upstream/4616793; hsa-let-7i/Downstream/11832828;
Nearest TSS
ENST00000382841/Upstream/170038; ENST00000500076/Downstream/146277;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/289193, chr12-CpG: 68/Downstream/204458
Upstream sequence
AGCCCTAGAACTGTCTTTGCCAATTAGAGATGTTCGCAAAGAAGTAGCAGCTCCGTGTGTTTTCTCTGTCCAGCTGCCTCTTACAGTATGTTTCTCAAAA
Downstream sequence
CAGCTTCCTAAGCTGGAGTATGGGCCTTTTAAGCTAATGCAATTTGTCTTCTTTGGCCTTTTAGTAGAACTTCTTCTGCTCCAAAATTAAATTGATCTTC
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate