Basic Information
VIS ID
TVIS10014783
Fusion event
HBV-chr10 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2654
Orient
+
Integrated sequence
TTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGGGCCCTCTTACAGTTAATGAAAAAAGGAGATTAAAATTAATTATGCCTGCTAGGTTCTAT| |CCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATA
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
1883909/1841715 (Hg38)
End
1883909/1841715 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-5699/Upstream/1199937; hsa-mir-107/Downstream/234304;
Nearest TSS
ENST00000439456/Upstream/104239; ENST00000435539/Downstream/171696;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/103891, chr10-CpG: 26/Downstream/473339
Upstream sequence
cacacgtttGAATTTCTCTACTTTAAATAAGCTTTTCTAAAATAAGTAACTACTATATAGCCATTAAGAATACAGAAAGTCTACAGGTACTGGCATAAAA
Downstream sequence
CAATTTGCAAAATATGTGGATAAGTGGAAAGAATCAAGAAGGAGAGTGCTGAGAATGGAACACATCAACAAAAGGATCCCCACACATGCatacatatgtg
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate