Basic Information
VIS ID
TVIS10014787
Fusion event
HBV-LOC105377567 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2712
Orient
-
Integrated sequence
GAAAAAAGGAGATTAAAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAAC| |ATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTG
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
181085995/180164842 (Hg38)
End
181085995/180164842 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377567
Nearest miRNA
hsa-mir-12113/Upstream/5740978; hsa-mir-1305/Downstream/2004451;
Nearest TSS
ENST00000502981/Upstream/699537; ENST00000512480/Downstream/594196;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/105376, chr4-CpG: 20/Downstream/1976283
Upstream sequence
tggtagacctgagatttgaaccagctgttagactccagagtcAGGTTGTGAAGCAAAGTGGATTTTTGACAGGAATAGAGTGGTTTTGTGTGTGTGTGCA
Downstream sequence
GCTGCCTGGAACACTGTGCAGGAAAAGGAATATGTGAAGCATGTCATAATCAGTCAGTTAGTTCTATCTGCCACAGATGAGGCATGAGAACTAGTAGCAT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate