VISDB Viral Integration Site DataBase

VIS ID

TVIS10014790

Fusion event

HBV-TERT integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

634

Orient

-

Integrated sequence

TGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGA| |TTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAG

Chromosome

chr5

Cytoband

p15.33

Reference genome

Start

End

1296151/1296036 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-138-5p ; hsa-mir-498 ; hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-512-5p ; hsa-mir-1207-5p ; hsa-mir-1266-5p ; hsa-mir-1182 ; hsa-mir-181a-5p ; hsa-mir-6776-3p ; hsa-mir-197-3p ; hsa-mir-6740-3p ; hsa-mir-6760-3p ; hsa-mir-532-5p ; hsa-mir-3064-5p ; hsa-mir-422a ; hsa-mir-346 ; hsa-mir-1226-3p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-143-3p ; hsa-mir-3161 ; hsa-mir-3605-5p ; hsa-mir-3620-3p ; hsa-mir-3682-3p ; hsa-mir-4323 ; hsa-mir-4712-3p ; hsa-mir-4733-3p ; hsa-mir-4758-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-7112-3p

Nearest miRNA

hsa-mir-4635/Upstream/233062; hsa-mir-10397/Downstream/13274;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/181, chr5-CpG: 18/Downstream/38926

Nearest cancer related gene

TERT(OG, No orient, 0)

Upstream sequence

accagcctggccaacatggagaaacctcgtctctactaaaattacaaaaattagtcagcatggtggtgggcgcctataattccagctacttgggaggctg

Downstream sequence

ACACGGCCACTGGTCCCCTCCAGACCTGGGGCCCCGGCACAACCGCAGGACAGCTGAGGACTTCCCAGGAATCCAGACTCCGGGTTGCTCAAGTTTGGAT