VISDB Viral Integration Site DataBase

VIS ID

TVIS10014799

Fusion event

HBV-NR1D2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2133

Orient

+

Integrated sequence

CGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGA| |CCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGA

Chromosome

chr3

Cytoband

p24.2

Reference genome

Start

End

24001271/23959780 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125a-5p ; hsa-mir-132-3p ; hsa-mir-10a-5p ; hsa-mir-744-5p ; hsa-mir-27a-3p ; hsa-mir-216a-3p ; hsa-mir-27b-3p ; hsa-mir-128-3p ; hsa-mir-513a-5p ; hsa-mir-3611 ; hsa-mir-3681-3p ; hsa-mir-509-3p ; hsa-mir-145-5p ; hsa-mir-766-3p ; hsa-mir-3925-3p ; hsa-mir-5195-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-601 ; hsa-mir-3683 ; hsa-mir-1273c ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-3185 ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p

Nearest miRNA

hsa-mir-12127/Upstream/3822139; hsa-let-7g/Downstream/1705093;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/13250, chr3-CpG: 135/Downstream/534573

Upstream sequence

GAAAGAACTGTTATTTCTGTCACAGAATAGTAATTTTATGTAGAAATTCTGCTAAGCTTAGCTAGTATGTTTTCTTCACTTCCTAGAAGAAAAGCTTACA

Downstream sequence

CAAAAAGTGTCTGTCTGTTGGAATGTCAAGAGATGGTATGTTCCCAGTTTAAAGAGTGTTCCTAAAGTGTATGGAGCTTGGCTTTTATTCCTCATCATGA