Basic Information
VIS ID
TVIS10014801
Fusion event
HBV-chr18 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1057
Orient
-
Integrated sequence
CCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGC| |CTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGCACCTTTACCCCGTTGCCCG
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
40716596/43136631 (Hg38)
End
40716596/43136631 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1-2/Upstream/3459852; hsa-mir-122/Downstream/1833451;
Nearest TSS
ENST00000575820/Upstream/20940; ENST00000591940/Downstream/135520;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/3294766, chr18-CpG: 180/Downstream/1542387
Upstream sequence
GAAAGACAAATTTTTTTCAATATATTTATCTGCCTCTCAATCTTATAGCCTCATAATCATATCTGGTATGATTGGACTGATATTTTTATAAGCAGATTAA
Downstream sequence
AACTCATTCACTCTAGTGAACATTATTCTTTAAAGCAGTCTCCATAGAACAGTATTATAGTTATTATAGCTGTTCATAAGGTGCACAAATATTTCAGAAC
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate