Basic Information
VIS ID
TVIS10014804
Fusion event
HBV-LOC105376988 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
504
Orient
+
Integrated sequence
TCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAG| |CACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATT
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
21222313/21180821 (Hg38)
End
21222313/21180821 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105376988
Nearest miRNA
hsa-mir-12127/Upstream/1043180; hsa-let-7g/Downstream/4484052;
Nearest TSS
ENST00000440867/Upstream/792572; ENST00000412369/Downstream/45484;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/994357, chr3-CpG: 86/Downstream/1191180
Upstream sequence
ACATCACAATATTCTTACATCTATTTCCATTGATAAATTAATAGAGGATCACTAATTGTGTAAGTTCTGATGAAAGAAAAAGCTTTTGCATCGCTGTAGA
Downstream sequence
cttgaagtaaaattactacatcaatgtgcataaacctttttgaaagctcttgatatatattgctgaaatgccctctaggtcgcctctagcaatttacact
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate