Basic Information
VIS ID
TVIS10014816
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
637
Orient
+
Integrated sequence
TCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTC| |CTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTA
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
95169110/94775334 (Hg38)
End
95169110/94775334 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7i/Upstream/203982; hsa-mir-1178/Downstream/59064;
Nearest TSS
ENST00000382841/Upstream/124772; ENST00000551792/Downstream/149472;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/124798, chr12-CpG: 119/Downstream/97722
Upstream sequence
TCTGAACATTCTGTGCTCTGTTCAAAAAAGGAAGGCTCTTCCTTTTCAGAGCCTAGATAAATTAGATAAAATGAACTTCCTAGCATAGAAAGCTGAATGT
Downstream sequence
CAAAAAAATCAATTCACATGACCTTACCAATGCAAAATACAAACCATGAAATGGTCTTAACATATCGAAGGCAGCATTTGCACTGTGGAGAAAAAGATAG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate