Basic Information
VIS ID
TVIS10014819
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AF533983.1
Start
1755
Orient
+
Integrated sequence
AAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCGTACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTA| |GGTTAATGATCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGT
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
58550781/58156998 (Hg38)
End
58550781/58156998 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1228/Upstream/332306; hsa-let-7i/Downstream/4103361;
Nearest TSS
ENST00000382841/Upstream/69106; ENST00000548969/Downstream/387126;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/220777, chr12-CpG: 100/Downstream/762780
Upstream sequence
agctaattctaacatatatgtcaattttggcttggttttgatggattgttctttttcttcatttttggttgtattttcctagttcttttcctgtctggta
Downstream sequence
attttttttcacgggaaagaaaatattgtgactttttccttgttgggtgctggatatctttttattcttattaatattcttgagttttgtttattggcaa
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate