Basic Information
VIS ID
TVIS10014821
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
483
Orient
+
Integrated sequence
TGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACT| |TCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCG
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
54834797/53968630 (Hg38)
End
54834797/53968630 (Hg38)
Orient
-
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/1255883; hsa-mir-1243/Downstream/6953989;
Nearest TSS
ENST00000502981/Upstream/267225; ENST00000595906/Downstream/29082;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/590400, chr4-CpG: 82/Downstream/95444
Upstream sequence
TCTTTTTTTTTGGTCAATCATATATGACCCAAATCAATATGACCAAAAAAATGAAAACATTTTTTCCTTATCTATATTTTTAGATTATTTGTTTATACCA
Downstream sequence
gtgatattccccttcctgtgtccaagtgttctcattgttcaattcctacccatgagtgagaacatgcagtgttcggtttttgtccttgtgatagtttgct
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate