Basic Information
VIS ID
TVIS10014824
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2368
Orient
+
Integrated sequence
AGTGTGGATTCGCACTCCTCCCGCTTACAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCT| |AGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCAT
Host Sequence
Chromosome
chr5
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
41551275/41551173 (Hg38)
End
41551275/41551173 (Hg38)
Orient
+
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/2993612; hsa-mir-103a-1/Downstream/12400331;
Nearest TSS
ENST00000502646/Upstream/40545; ENST00000505931/Downstream/188548;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/40624, chr5-CpG: 104/Downstream/318388
Upstream sequence
cttttagcgtttctcaacacagggatcactacatattttacttttttgaatgttgtctgtctccccgcaaataaaataactccaggaggacagcggtttt
Downstream sequence
tgtggaaaacagtttggagatttcttaaagaacttaaaacggaagtaccattcagcccaacaatcccattaatcagtatatatccaaaggaatataaatt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate