VISDB Viral Integration Site DataBase

VIS ID

TVIS10014827

Fusion event

HBV-REXO1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1419

Orient

+

Integrated sequence

ACTTATCGGGACTGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTCCCATGGCTGCTCGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC| |TTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCA

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

1840674/1840675 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-484 ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-6810-5p ; hsa-mir-491-5p ; hsa-mir-92a-2-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-4664-5p ; hsa-mir-4652-5p ; hsa-mir-342-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-25-5p ; hsa-mir-6820-5p ; hsa-mir-658 ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-6782-5p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-6081 ; hsa-mir-4707-3p ; hsa-mir-2467-3p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-7114-3p ; hsa-mir-4468 ; hsa-mir-1180-5p ; hsa-mir-551b-3p ; hsa-mir-551a ; hsa-mir-7108-3p ; hsa-mir-662 ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-195-5p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1203 ; hsa-mir-1251-5p ; hsa-mir-1301-5p ; hsa-mir-1909-3p ; hsa-mir-3151-5p ; hsa-mir-3165 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3190-3p ; hsa-mir-3196 ; hsa-mir-328-5p ; hsa-mir-3656 ; hsa-mir-4283 ; hsa-mir-4285 ; hsa-mir-4446-3p ; hsa-mir-4467 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-4508 ; hsa-mir-4651 ; hsa-mir-4669 ; hsa-mir-4721 ; hsa-mir-4722-5p ; hsa-mir-4731-5p ; hsa-mir-4768-3p ; hsa-mir-4781-5p ; hsa-mir-486-3p ; hsa-mir-5001-5p ; hsa-mir-504-3p ; hsa-mir-5787 ; hsa-mir-6079 ; hsa-mir-6087 ; hsa-mir-608 ; hsa-mir-6132 ; hsa-mir-637 ; hsa-mir-6502-5p ; hsa-mir-671-5p ; hsa-mir-6722-3p ; hsa-mir-6733-3p ; hsa-mir-6795-5p ; hsa-mir-6804-5p ; hsa-mir-6816-3p ; hsa-mir-6816-5p ; hsa-mir-6822-3p ; hsa-mir-6828-5p ; hsa-mir-6836-5p ; hsa-mir-6847-5p ; hsa-mir-6880-5p ; hsa-mir-6885-5p ; hsa-mir-6887-5p ; hsa-mir-7109-5p ; hsa-mir-7154-3p ; hsa-mir-7-5p ; hsa-mir-762 ; hsa-mir-8071 ; hsa-mir-92b-5p

Nearest miRNA

hsa-mir-1302-11/Upstream/24437; hsa-let-7e/Downstream/393387;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/12128, chr19-CpG: 20/Downstream/7015

Upstream sequence

AAACTCCTATTCATCCTCCAAAACCCAGCCCAGTAATCCTGTGTTTGGAAACACTCGCCCCACCCCCCTGCAACTCTGAGTGACACCCGGGCCCGCCCCA

Downstream sequence

CGTCACCCCTCCACTCCCTGCAACTCCAAGTGACAGCTGCCCTGTCTCCTGGACCCGGGCCCACCCCACATCACCCCCTCCGCTTCTGCTTCCCGAGTCC