Basic Information
VIS ID
TVIS10014828
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1820
Orient
+
Integrated sequence
GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAA
Host Sequence
Chromosome
chr5
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
129990968/130655275 (Hg38)
End
129990968/130655275 (Hg38)
Orient
+
Fragile sites / regions
FRA5C
Nearest miRNA
hsa-mir-10397/Upstream/1258128; hsa-mir-103a-1/Downstream/1562574;
Nearest TSS
ENST00000502646/Upstream/747188; ENST00000507584/Downstream/507352;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/749356, chr5-CpG: 27/Downstream/339803
Upstream sequence
TTAATACCACCTAGAAATCTAGAAATAAAACTAATTTCTGCAAATTATAATTTTTAAAGATTTTTATTCATAAGTGTGTTTTCTATTATAACACAGACCT
Downstream sequence
ATGTCTGCTGTATAAACAGTGTGTTCAGTCTGTGTATATCAAATATCTCAGACACAATGATCAACAGCAATTTCAGACACATGGACATATTAGGCATATG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate