Basic Information
VIS ID
TVIS10014829
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2115
Orient
-
Integrated sequence
GGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGT| |GGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATT
Host Sequence
Chromosome
chr5
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
129991025/130655332 (Hg38)
End
129991025/130655332 (Hg38)
Orient
-
Fragile sites / regions
FRA5C
Nearest miRNA
hsa-mir-10397/Upstream/1258185; hsa-mir-103a-1/Downstream/1562517;
Nearest TSS
ENST00000502646/Upstream/747245; ENST00000507584/Downstream/507295;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/749413, chr5-CpG: 27/Downstream/339746
Upstream sequence
AGATTTTTATTCATAAGTGTGTTTTCTATTATAACACAGACCTGGTTTTGTAACAGAATTCAACAGAAAAAAAAAGGGAATTATTTTAAGCAGCTCTACT
Downstream sequence
TGATCAACAGCAATTTCAGACACATGGACATATTAGGCATATGtttattttattagttatttttaaattgatcttaaaatttctacagtgcataatacgg
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate