VISDB Viral Integration Site DataBase

VIS ID

TVIS10014830

Fusion event

HBV-chr7 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

277

Orient

+

Integrated sequence

CCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTT| |CTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTATCGCTGGA

Chromosome

chr7

Cytoband

q32.1

Reference genome

Start

End

128664866/129024812 (Hg38)

Orient

-

Location type

Intronic

Target gene

LOC100132905 ; TNPO3

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-423-3p ; hsa-mir-149-5p ; hsa-mir-15b-5p ; hsa-mir-17-5p ; hsa-mir-210-3p ; hsa-mir-6776-5p ; hsa-mir-7977 ; hsa-mir-143-5p ; hsa-mir-4284 ; hsa-mir-6499-3p ; hsa-mir-20b-3p ; hsa-mir-5693 ; hsa-mir-383-3p ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-629-3p ; hsa-mir-665 ; hsa-mir-711 ; hsa-mir-7160-5p ; hsa-mir-3934-3p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-767-3p ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-4695-5p ; hsa-mir-6808-5p ; hsa-mir-4684-5p ; hsa-mir-6771-3p ; hsa-mir-3675-3p ; hsa-mir-548c-3p ; hsa-mir-6516-3p ; hsa-mir-1257 ; hsa-mir-4286 ; hsa-mir-3607-5p ; hsa-mir-4760-3p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-345-3p ; hsa-mir-4319 ; hsa-mir-4732-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-6515-3p ; hsa-mir-670-5p ; hsa-mir-6749-3p ; hsa-mir-7113-3p

Nearest miRNA

hsa-mir-10525/Upstream/816869; hsa-mir-10399/Downstream/745571;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/86110, chr7-CpG: 60/Downstream/29647

Upstream sequence

ggtgtttgtagtaatctctgatggtagtttgtatttctgtgggatcggtggtgatatcccctttatcgttttttattgcgtctatttgattcttctctct

Downstream sequence

caggagtttgagaccagcctctatgaaaaatttttgaaaaatctgccacgtgtggtggcatgccccttagtcccagctactcaggaggctgaggggaagg