Basic Information
VIS ID
TVIS10014831
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2507
Orient
-
Integrated sequence
TCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCATAAGGTGGGAAACTTTACTGGGCTTTATTCTTCTACTGTA| |CCTGTCTTTAATCCTGAGTGGCAAACTCCCTCCTTTCCTAACATTCATTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGGGCCCTCTTACAG
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
41308707/41451188 (Hg38)
End
41308707/41451188 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-124-1/Upstream/180045; hsa-mir-10400/Downstream/209253;
Nearest TSS
ENST00000518652/Upstream/15890; ENST00000523420/Downstream/39208;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/141567, chr8-CpG: 69/Downstream/39087
Upstream sequence
atcccagcactttgggaggccgaggcgggcggatcacctgagattaggagttcgagaccagcctggccaacatggtgaaaccccgtctctactaaaaata
Downstream sequence
tggtgaaaactcgtctttactaaaaatacaaaaattagctgggtgtggtggcaggcacctgtaattccagctacacgggaggctgatgcaggagaatcac
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate