Basic Information
VIS ID
TVIS10014832
Fusion event
HBV-CDRT7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1139
Orient
+
Integrated sequence
GCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGCA| |CCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACTGGATGGGGCTTGGCCATAGGCCATCGGCGCATGCGT
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
14933986/15030669 (Hg38)
End
14933986/15030669 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
CDRT7
Nearest miRNA
hsa-mir-1253/Upstream/1487023; hsa-mir-10226/Downstream/220958;
Nearest TSS
ENST00000595228/Upstream/15864; ENST00000568256/Downstream/306;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/685265, chr17-CpG: 77/Downstream/229944
Upstream sequence
CCACTTTAACTCTGTAAGTTATAAGTAAATTATATAtatatatatataatcactttaactctataagctataagtaactcatatgattctcataacaacc
Downstream sequence
ttagagaaaaatactatggtagtctccattttacagatgcaaaacctggggtgcagaTTTTAATCAacttgcccaaggtcccatagacaataactgctgg
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate