Basic Information
VIS ID
TVIS10014834
Fusion event
HBV-LOC400655 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1774
Orient
+
Integrated sequence
CAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACT| |AGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCA
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
70874013/73206778 (Hg38)
End
70874013/73206778 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC400655
Nearest miRNA
hsa-mir-1-2/Upstream/353396;
Nearest TSS
ENST00000575820/Upstream/337738; ENST00000581467/Downstream/508712;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/337142, chr18-CpG: 97/Downstream/940542
Upstream sequence
ATGCACCTCTATGTGTAACTCTTCCATATGCTGGACACTTAGGAAAATAAATTTCTTATTGCACCTAATAATTTAAGAACACAAATGCAGAGAGTTTATA
Downstream sequence
AAACTTTTTGGCACCAAATGCTTTGGAAAATAGCTTATTCCTTATACAAAGCATTCAAGAATGGTAGAAAAGTATACTAGATAAAATAAAGTCACCAAAA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate