VISDB Viral Integration Site DataBase

VIS ID

TVIS10014835

Fusion event

HBV-ORC5 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2066

Orient

-

Integrated sequence

TTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTTTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCA| |GGCAAGCTGTTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTCAGCTATGT

Chromosome

chr7

Cytoband

q22.1

Reference genome

Start

End

103802548/104162100 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-6829-5p ; hsa-mir-6762-3p ; hsa-mir-564 ; hsa-mir-5580-5p ; hsa-mir-3692-5p ; hsa-mir-330-3p ; hsa-mir-4446-3p

Nearest miRNA

hsa-mir-10525/Upstream/1690569; hsa-mir-10399/Downstream/10491245;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/171833, chr7-CpG: 88/Downstream/166330

Upstream sequence

CAATGAGAACAGTCAACATAATAACCCTAACAGTgttagggttaggggttaggggttagggttagggttagggttagggttagggttagggttagggtta

Downstream sequence

TAATTCATGTCATCAGAAACGAGACAATGCTCAAGTTCCATTCTATTAGCAGATAATTTTAATAGCCAATAAATAtttatttctttttttgagacagagc