Basic Information
VIS ID
TVIS10014843
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25636086
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
981
Integrated sequence
ATATGTAATTGGAAGTTGGGGTACTTTACCACAGGAACATATTGTACGGAAACTCAAGCAATGTTTTCGAAAACTGCCTGTAAATAGACCTATTGATTGG| |AAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTA
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
14604475/14464351 (Hg38)
End
14604475/14464351 (Hg38)
Nearest miRNA
hsa-mir-3125/Upstream/1726907; hsa-mir-10b/Downstream/4884078;
Nearest TSS
ENST00000437798/Upstream/63388; ENST00000450715/Downstream/152077;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1745458, chr2-CpG: 248/Downstream/167902
Upstream sequence
agaatagatattcagtattcttacaacacacacagacacacacacacacaggtatgtcaggtgatggatatgtcaattagcttgattgtggtgatcattt
Downstream sequence
ttataatatatacatatatcaaaataGTATATTTCCAGTTTTTCACTTTTCttttaatttttattatcatatattttactatataaaatatttttaaCTA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun ,2015,6: 6120.
Curate