Basic Information
VIS ID
TVIS10014844
Fusion event
HBV-chr4 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25636086
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1741
Integrated sequence
CCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTT| |GGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCA
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
63879681/63013963 (Hg38)
End
63879681/63013963 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/2091279; hsa-mir-1243/Downstream/3262861;
Nearest TSS
ENST00000502981/Upstream/848409; ENST00000507857/Downstream/114348;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1810880, chr4-CpG: 60/Downstream/335166
Upstream sequence
aaattttactacatgatctaacagtcatacccatgatttgatctttgttccaaggctacatcagacggtcactgccctaatttgtagagaaatatttcca
Downstream sequence
acaatctgaaaaagaattcaaggacataatcccattttaaacagcgacaagtgaaataaaatatctgggaataaacttaaccaacaaagtgaaagatttc
Reference
Fujimoto, A., et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun ,2015,6: 6120.
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