Basic Information
VIS ID
TVIS10014850
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25636086
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2307
Integrated sequence
TTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTTGAGTATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCCGCTTACAGACCACCAAA| |TGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAA
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
104316887/103664537 (Hg38)
End
104316887/103664537 (Hg38)
Nearest miRNA
hsa-mir-1297/Upstream/1618533; hsa-mir-1267/Downstream/3866634;
Nearest TSS
ENST00000623511/Upstream/239337; ENST00000640578/Downstream/1801330;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/818124, chr13-CpG: 29/Downstream/2828523
Upstream sequence
CTACTTTCTAAAGTTTTTCACTTTTGAATTGAAGTTCTTGAGATGTtttctgggttttccttgaaggggtcaactcataagtctgaaaattaatcaaaca
Downstream sequence
tagctaagatgttcaaaatgttcttggcagagaaaataaatgttcacAATCTCATATTCTTTCCAACATTCATACTGGAGGTTTAGTGGATCTTTATCAA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun ,2015,6: 6120.
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