Basic Information
VIS ID
TVIS10014853
Fusion event
HBV-chr15 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25636086
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2729
Integrated sequence
ATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTAC| |TTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTT
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
48094848/47802651 (Hg38)
End
48094848/47802651 (Hg38)
Nearest miRNA
hsa-mir-10393/Upstream/2369522; hsa-mir-11181/Downstream/1366419;
Nearest TSS
ENST00000557528/Upstream/36071; ENST00000558370/Downstream/42305;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/83804, chr15-CpG: 53/Downstream/375159
Nearby gene
LINC01491(+733) ;
Upstream sequence
CTTGGGAAATCCATCTCATTATTCTAGGGACAAACAAGGCTGAAGTCCATGAGGGCAGGGGAGTAATAGTAGAGGGAGCAGTAGGTTGAGAGGAGAGAAT
Downstream sequence
TGTTAATAATAATAGTTGTTCTGAATCCAGCTGTTTATGCATGAATCAGACTTGTGCATGTCTTCTAGTAGTCAATTCTTTCCATCTCTCAGGTGCTCTG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun ,2015,6: 6120.
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