Basic Information
VIS ID
TVIS10014854
Fusion event
HBV-chr15 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25636086
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1818
Integrated sequence
TTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
48094912/47802715 (Hg38)
End
48094912/47802715 (Hg38)
Nearest miRNA
hsa-mir-10393/Upstream/2369586; hsa-mir-11181/Downstream/1366355;
Nearest TSS
ENST00000557528/Upstream/36135; ENST00000558370/Downstream/42241;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/83868, chr15-CpG: 53/Downstream/375095
Nearby gene
LINC01491(+669) ;
Upstream sequence
AATAGTAGAGGGAGCAGTAGGTTGAGAGGAGAGAATTGTTAATAATAATAGTTGTTCTGAATCCAGCTGTTTATGCATGAATCAGACTTGTGCATGTCTT
Downstream sequence
CTAGTAGTCAATTCTTTCCATCTCTCAGGTGCTCTGTGTTTTTATATTGTTACTATTGTTCATTATCATTATTATGGCAGTTAGGATATAAGATTTGGGG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun ,2015,6: 6120.
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