VISDB Viral Integration Site DataBase

VIS ID

TVIS10014855

Fusion event

HBV-CMIP integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Reference genome

Start

428

Integrated sequence

AATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTATCGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCA| |TCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCAC

Chromosome

chr16

Cytoband

q23.2

Reference genome

Start

End

81543548/81509943 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-33a-5p ; hsa-mir-302a-5p ; hsa-let-7c-3p ; hsa-mir-3924 ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-3529-3p ; hsa-mir-3121-3p

Nearest miRNA

hsa-mir-1225/Upstream/124850; hsa-mir-11401/Downstream/23959;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/64349, chr16-CpG: 39/Downstream/168316

Upstream sequence

GAACAGGTGAGTTTCCTGGTGGGCAGGAGCATGGAAGTGTGATGGATCTGATGCAGTGATTGGCTGGGGGCCCCTTTGTCAGGAGCTCCGGACATCCTGC

Downstream sequence

CCTCACGGAGAAGTCCTGCCCCAAAGGAAGTATGCCTGAATCAGACCTGGCTGGCAAATTGAACCTCATTTTCTGATCAATTTCCATCAGGATTTTAGAT