Basic Information
VIS ID
TVIS10014856
Fusion event
HBV-chrX integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25636086
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1810
Integrated sequence
AAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGC| |ACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTG
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
25471062/25452945 (Hg38)
End
25471062/25452945 (Hg38)
Nearest miRNA
hsa-mir-23c/Upstream/5435758; hsa-let-7f-2/Downstream/3042610;
Nearest TSS
ENST00000429181/Upstream/436525; ENST00000423914/Downstream/425394;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/429700, chrX-CpG: 30/Downstream/1104696
Upstream sequence
ATACGACACATTCTTAGTtcccagtactttgggaggtcatggtgggagaatcacttgagcccaggagttcgagaatagccagggcaacatatgaagacct
Downstream sequence
ATTTTAAAGTTTTTGAATCAGAGcaatggtgtgctggtaaatgtttaaaaaaagggatcttaattttcaaaatgccccaatttggagtgtctgttgattt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. Nat Commun ,2015,6: 6120.
Curate