Basic Information
VIS ID
TVIS10014862
Fusion event
HBV-chr6 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634756
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1470
Integrated sequence
TCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGC| |CGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGC
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
68664024/67954132 (Hg38)
End
68664024/67954132 (Hg38)
Nearest miRNA
hsa-mir-10398/Upstream/10563920; hsa-mir-10524/Downstream/3422828;
Nearest TSS
ENST00000381078/Upstream/64793; ENST00000449928/Downstream/101219;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1859194, chr6-CpG: 37/Downstream/680708
Upstream sequence
tcccttttggaatggaaatgtgtatcctatgcctgtcctaccgttgtatcttggaagtagataaattgttttcgcaggatcacagataagactttggact
Downstream sequence
TTCTACAACTGCAAGCTGTTTCTCAGCCTAAGGAGATTTCTTTAGGCTGAGAGCTATCAAGAGTTGAAAATGAATTAAGCCCCATCCCCTGGAGTTCAAT
Reference
Fujimoto, A., et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet,2012, 44(7): 760-764.
Curate