Basic Information
VIS ID
TVIS10014868
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634756
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
2622
Integrated sequence
GATTGGAAAACTCCCTCCTTTCCTCACATTCATTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGGGCCCTCTGACAGTTAATGAAAAAAGGA| |GATTAAAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGACAAAGGCATTAAACCGTATTATCCTGAATATGCAGTTAA
Host Sequence
Chromosome
chr7
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
52802387/52734693 (Hg38)
End
52802387/52734693 (Hg38)
Nearest miRNA
hsa-mir-1183/Upstream/7852893; hsa-mir-10399/Downstream/4221092;
Nearest TSS
ENST00000635602/Upstream/541780; ENST00000408890/Downstream/300949;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/460123, chr7-CpG: 52/Downstream/300889
Upstream sequence
ACAGCATCTCTTCAAGTGAAGACTTCAGAGAAAGCTGCAAACAGAAATGACAAaaaacaaaacaaaacaaaacaaaacaaaaaaaaacaGGGCAATAAAC
Downstream sequence
GAATAAACAGAATAACAATACAGCAAACAAACTAGGTTTTCTTTTTAAGTGCCATCTCCTGGAGAAAGAGGTCAGGCTGAGAAATGCCCTCTATTCTCAC
Reference
Fujimoto, A., et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet,2012, 44(7): 760-764.
Curate