Basic Information
VIS ID
TVIS10014872
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634756
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1895
Integrated sequence
GGTCTGTTCACCAGCACCATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT| |GGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGA
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
70267023/70802037 (Hg38)
End
70267023/70802037 (Hg38)
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/3687640; hsa-mir-10399/Downstream/505635;
Nearest TSS
ENST00000635602/Upstream/15116; ENST00000447516/Downstream/330132;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/11037, chr7-CpG: 237/Downstream/329205
Nearby gene
AUTS2(No orient, 9137)
Upstream sequence
tacagtgaggattctgagaatctacaaggccatgtgtttcaaaactattaggaggcagtgccagactcaggtctgactcgaggtggatgcccttagccat
Downstream sequence
GTGGGTGGCAGTCATGCCTGAGAGTTGGCTTGTCCAAGACTGATTTCCTTCAGGCTGGCCTGTGAAACTCTGAAAACCAGCTATAATACAAAGCTTAAAG
Reference
Fujimoto, A., et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet,2012, 44(7): 760-764.
Curate