Basic Information
VIS ID
TVIS10014875
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634756
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1411
Integrated sequence
GGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCG| |GGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCG
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1310429/1310314 (Hg38)
End
1310429/1310314 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-4457/Upstream/937; hsa-mir-10397/Downstream/200448;
Nearest TSS
ENST00000502646/Upstream/15245; ENST00000605200/Downstream/11515;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/14459, chr5-CpG: 18/Downstream/24648
Nearby gene
TERT
Upstream sequence
GGGGCCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAgggcggggccgcggaaaggaaggggaggggctggg
Downstream sequence
ctccagctccatctcctcgccccagggagacgaccaggtccagcctcaggtgggcaccattgcccggacagtcttcccaggtaagcgattgtaggcttgc
Reference
Fujimoto, A., et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet,2012, 44(7): 760-764.
Curate