VISDB Viral Integration Site DataBase

VIS ID

TVIS10014876

Fusion event

HBV-TVP23C integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1675

Integrated sequence

CGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTC| |AGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTA

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

15412626/15509312 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-376a-2-5p ; hsa-mir-3935 ; hsa-mir-3674 ; hsa-mir-3658 ; hsa-mir-29b-2-5p ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-4775 ; hsa-mir-3653-3p ; hsa-mir-299-5p ; hsa-mir-24-2-5p ; hsa-mir-24-1-5p ; hsa-mir-509-3p ; hsa-mir-935 ; hsa-mir-6512-5p ; hsa-mir-376c-3p ; hsa-mir-5683 ; hsa-mir-338-5p ; hsa-mir-3978 ; hsa-mir-32-3p ; hsa-mir-1287-3p ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-5699-5p ; hsa-mir-875-3p ; hsa-mir-6793-3p ; hsa-mir-6769a-3p ; hsa-mir-4323 ; hsa-mir-3943 ; hsa-mir-5582-3p ; hsa-mir-651-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6771-5p ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-20b-3p ; hsa-mir-6746-5p ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-5690 ; hsa-mir-7977 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-3622b-5p ; hsa-mir-6720-3p ; hsa-mir-668-5p ; hsa-mir-4787-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6880-5p ; hsa-mir-4653-3p ; hsa-mir-4252 ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-1292-3p ; hsa-mir-4684-5p ; hsa-mir-4755-3p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-4793-5p ; hsa-mir-3613-3p ; hsa-mir-6502-3p ; hsa-mir-433-5p ; hsa-mir-6771-3p ; hsa-mir-548c-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4470 ; hsa-mir-661 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-759 ; hsa-mir-5586-3p ; hsa-mir-508-5p ; hsa-mir-4797-5p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3612 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-383-3p ; hsa-mir-3913-5p ; hsa-mir-3937 ; hsa-mir-4459 ; hsa-mir-450a-1-3p ; hsa-mir-4728-5p ; hsa-mir-6087 ; hsa-mir-650 ; hsa-mir-6513-5p ; hsa-mir-658 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6808-5p ; hsa-mir-6883-5p ; hsa-mir-6893-5p ; hsa-mir-7106-5p ; hsa-mir-887-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-1253/Upstream/257616; hsa-mir-10226/Downstream/772702;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/167503, chr17-CpG: 71/Downstream/53733

Upstream sequence

AATAAACACAACCTCTAACAGAGGGAGGCGCCTGGCACCAACCAACCAGTCAGaaggacctggaggctctgggttcagcccacataaaccccttagttgc

Downstream sequence

tggaccaaggggaggtggtagggggacagcccaggggacaggatgcacttgggaggcctggagcagctgctggctacaactagtcaggaaatactttaga