VISDB Viral Integration Site DataBase

VIS ID

TVIS10014877

Fusion event

HBV-TTLL9 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2716

Integrated sequence

AAAGGAGATTAAAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGACAAAGGCATTAAACCGTATTATCCTGAATATGC| |AGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCCTCATTTTGTGGG

Chromosome

chr20

Cytoband

q11.21

Reference genome

Start

End

30502092/31914289 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6722-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4533 ; hsa-mir-9500 ; hsa-mir-6888-5p ; hsa-mir-552-3p ; hsa-mir-4428

Nearest miRNA

hsa-mir-103a-2/Upstream/307049; hsa-mir-1-1/Downstream/323506;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/34127, chr20-CpG: 53/Downstream/37431

Upstream sequence

TTTCACTGAGACTTTCTAAGAGTCGGGATGCTTTACTCAGTAAATAATAGAAAATCCAAATAACAGTAGCTTAAACAAGAGGGcaagacttctgtactgt

Downstream sequence

ttttatgccatgggcctctttgacatctggtgaaatgtgtggaccctatcacagaatagtggtgtttttttaaccacttcattgaaacataattggcgta