Basic Information
VIS ID
TVIS10014878
Fusion event
HBV-chr9 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634756
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1814
Integrated sequence
CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCA| |TGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCC
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
24396870/24396872 (Hg38)
End
24396870/24396872 (Hg38)
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/2884687; hsa-let-7a-1/Downstream/4466754;
Nearest TSS
ENST00000422679/Upstream/498818; ENST00000602614/Downstream/148804;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/545348, chr9-CpG: 111/Downstream/1280624
Nearby gene
IZUMO3(No orient, 146342)
Upstream sequence
TCTTTTGGACAGTAATTAAGCATAATAATTTATAGACTGATTCGGTAATTTTATTCTCTAGAATTTCTAATTATTCAACAAACAATATATGCACAGAACA
Downstream sequence
ttgcaggcagtctatcgtgggactttaccttgtgactgtgtgagtcaatcctccttaataaacttcctttcatatatacatatatcctattagttctgtc
Reference
Fujimoto, A., et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet,2012, 44(7): 760-764.
Curate