VISDB Viral Integration Site DataBase

VIS ID

TVIS10014880

Fusion event

HBV-CHIC2 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2014

PubMed ID

Virus name

HBV

Reference genome

Region type

Surface

Start

467

End

711

Orient

+

Integrated sequence

CCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAGAACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTT

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

54915241/54049074 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-124-3p ; hsa-mir-29c-3p

Nearest miRNA

hsa-mir-12113/Upstream/1329866; hsa-mir-1243/Downstream/6873545;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/664383, chr4-CpG: 82/Downstream/15000

Downstream sequence

GAGAGACATAGCAGGCATTGAAACAATGGAAATGCCCACATA

Target sequence

AGAGACATAGCAGGCATTGAAACAATGGAAATGCCCACATAGCAGAAGGGAGTGAGGGGATCCAAACTACAAGAGCGACAAAATCAACTGTGGATCCAGAGACGAAAAAATGTTCTGTAGTGCAAAGGTAATCTGGTGAGAATGATGAAAAAAAAAGAACCATTTTTAGAAAAAAGGAATATTAGAAATATTGAAGTAAATATCATAAGTCATTCTATTACAAAGGCATTAACTCCTTCCTATCAATAGAATGTA

Junction sequence