VISDB Viral Integration Site DataBase

VIS ID

TVIS10014889

Fusion event

HBV-TPCN2 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2014

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase

Start

1095

End

1164

Orient

+

Integrated sequence

TTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGT

Chromosome

chr11

Cytoband

p15.2

Reference genome

Start

End

14159048/14137544 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-3163 ; hsa-mir-6127 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6748-5p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-4481 ; hsa-mir-4745-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6871-5p ; hsa-mir-4284 ; hsa-mir-2276-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6890-3p ; hsa-mir-122-3p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-8070 ; hsa-mir-3161 ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-3692-3p ; hsa-mir-4504 ; hsa-mir-549a ; hsa-mir-603 ; hsa-mir-3529-3p ; hsa-mir-6086 ; hsa-mir-377-5p

Nearest miRNA

hsa-mir-210/Upstream/1973735; hsa-let-7a-2/Downstream/1831989;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/172700, chr11-CpG: 33/Downstream/121651

Downstream sequence

GGGTCCAGGAGGGCCCAGGAGGTAGGGAGGGGAGGA

Target sequence

CGCCCCCCTCACATCTAGGCTGAGGATGCTATTATTATCCCA

Junction sequence