VISDB Viral Integration Site DataBase

VIS ID

TVIS10014894

Fusion event

HBV-CGN integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2829

Orient

-

Integrated sequence

ACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTC| |TTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACAC

Chromosome

chr1

Cytoband

q21.3

Reference genome

Start

End

151503456/151530980 (Hg38)

Orient

-

Location type

Promoter

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-186-5p ; hsa-mir-19b-3p ; hsa-mir-7110-3p ; hsa-mir-6793-3p ; hsa-mir-4705 ; hsa-mir-6771-3p ; hsa-mir-1270 ; hsa-mir-143-5p ; hsa-mir-185-5p ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-3663-5p ; hsa-mir-3944-5p ; hsa-mir-4306 ; hsa-mir-451b ; hsa-mir-4531 ; hsa-mir-4644 ; hsa-mir-5192 ; hsa-mir-548e-5p ; hsa-mir-6131 ; hsa-mir-620 ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-101-1/Upstream/978966; hsa-mir-1182/Downstream/14816;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/19338, chr1-CpG: 56/Downstream/9205

Upstream sequence

ctgtaattccagcactttgagaggctgaggtaggcagatacccgaggtcaggagtttgagaccagcctggccaacatagcaaaactctgtctctactaaa

Downstream sequence

aatacaaaaaattagccgggcttggtggctcatgcctgtagtcccagctactcaggagggtgatgcaggagagtcacttgcacccggaaggtggaggttg