VISDB Viral Integration Site DataBase

VIS ID

TVIS10014895

Fusion event

HBV-chr1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp4 precore/core protein

Start

2332

Orient

+

Integrated sequence

GGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTC| |CGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCA

Chromosome

chr1

Cytoband

q21.3

Reference genome

Start

End

151509234/151536758 (Hg38)

Orient

-

Location type

Promoter

Fragile sites / regions

Target gene

CGN ; TUFT1

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-186-5p ; hsa-mir-19b-3p ; hsa-mir-330-5p ; hsa-mir-195-5p ; hsa-mir-6510-3p ; hsa-mir-4668-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6888-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-542-3p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-4522 ; hsa-mir-3120-5p ; hsa-mir-766-3p ; hsa-mir-4330 ; hsa-mir-6849-3p ; hsa-mir-759 ; hsa-mir-5586-3p ; hsa-mir-3664-5p ; hsa-mir-508-5p ; hsa-mir-7110-3p ; hsa-mir-6793-3p ; hsa-mir-4705 ; hsa-mir-6771-3p ; hsa-mir-1270 ; hsa-mir-143-5p ; hsa-mir-185-5p ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-3663-5p ; hsa-mir-3944-5p ; hsa-mir-4306 ; hsa-mir-451b ; hsa-mir-4531 ; hsa-mir-4644 ; hsa-mir-5192 ; hsa-mir-548e-5p ; hsa-mir-6131 ; hsa-mir-620 ; hsa-mir-9-5p ; hsa-mir-1273g-3p ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-4797-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p

Nearest miRNA

hsa-mir-101-1/Upstream/984744; hsa-mir-1182/Downstream/9038;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/25116, chr1-CpG: 56/Downstream/3427

Upstream sequence

TGTTATGGGGGAGGGTCCCAGGCCATGGTAGTAGATGCTATTCAGATGTGTGGACTTGGTATCCTGCCCAGCTAAGCCTGAGGGTGAAGGCTTTGAAGCG

Downstream sequence

TCAGGTGGATGAAGCAGAAGAGGAAATTGAGCGACTGGACGGCCTGAGGAAGAAGGCCCAGCGTGAGGTGGAGGAGCAGCATGAGGTCAATGAACAGCTC