Basic Information
VIS ID
TVIS10014899
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S1/pre-S2/S
Start
2907
Orient
-
Integrated sequence
CATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGG| |ATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGG
Host Sequence
Chromosome
chr1
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
207462631/207289286 (Hg38)
End
207462631/207289286 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/814422; hsa-mir-1182/Downstream/512566;
Nearest TSS
ENST00000473358/Upstream/40219; ENST00000343420/Downstream/32090;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/235789, chr1-CpG: 71/Downstream/31912
Upstream sequence
gcttttattctcactgaacttaaaatcttgtggggaatttggacaagtaaataggaaatcaaagctcagtgctttgatgaaaaggtataaagatcatggg
Downstream sequence
gtcacttgacctaattcaggggatcagagaagacatccatgaagaagtggtactcacacaaagtcctgaagaatgaAAAACAATGCATATGCAAAGGCCA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate