VISDB Viral Integration Site DataBase

VIS ID

TVIS10014902

Fusion event

HBV-SREK1IP1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2616

Orient

+

Integrated sequence

TTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGA| |GAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACAT

Chromosome

chr5

Cytoband

q12.3

Reference genome

Start

End

64014600/64718773 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-101-3p ; hsa-mir-26b-5p ; hsa-let-7d-5p ; hsa-mir-935 ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-mir-21-3p ; hsa-mir-495-3p ; hsa-mir-3591-3p ; hsa-mir-5688 ; hsa-mir-4452 ; hsa-mir-501-5p ; hsa-mir-335-3p ; hsa-mir-183-3p ; hsa-mir-137 ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-590-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-4668-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-4799-5p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-561-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-8086 ; hsa-mir-194-3p ; hsa-mir-3922-5p ; hsa-mir-4519 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-2909 ; hsa-mir-3187-3p ; hsa-mir-4662a-5p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-4529-5p ; hsa-mir-103b ; hsa-mir-628-5p ; hsa-mir-8075 ; hsa-mir-3121-5p ; hsa-mir-500a-5p

Nearest miRNA

hsa-mir-10397/Upstream/5015070; hsa-mir-103a-1/Downstream/7450694;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/27626, chr5-CpG: 25/Downstream/49643

Upstream sequence

TGCGTGCGGCGACCCTTTGGCCGCTGGCCTGATCCGGAGACCCAGGGCTGCCTCCAGGTCCGGACGCGGGGCGTCGGGCTCCGGGCACCACGAATGCCGG

Downstream sequence

GGTTTTGTAACAGAATTCAACAGAAAAAAAAAGGGAATTATTTTAAGCAGCTCTACTGAGCATATCTACTATGTCCTGTAGTTTTTGTAGTCAGAAACTA