VISDB Viral Integration Site DataBase

VIS ID

TVIS10014905

Fusion event

HBV-ELMO1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2256

Orient

+

Integrated sequence

AGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTAT| |TTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGAC

Chromosome

chr7

Cytoband

p14.2

Reference genome

Start

End

37017918/36978313 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6793-3p ; hsa-mir-4267 ; hsa-mir-6736-3p ; hsa-mir-1226-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p

Nearest miRNA

hsa-mir-1183/Upstream/58881; hsa-mir-10399/Downstream/6172582;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/588116, chr7-CpG: 136/Downstream/469438

Upstream sequence

CAATTGCCACATCAAATTCCCATGACCAAAGAGGGCACTAAATGAACAGGGCccagcctgggccacatagtgagactctgcctctacaaaaaaaaaatat

Downstream sequence

CTCAGGTTACTTCAAGATCTAGGATGCTATAAGTTCACAGTAAATAGATGTCCAGATGTGACAGAGAAAGAAATCACCCCTTCTCCTCTCTTGACAGAAT