VISDB Viral Integration Site DataBase

VIS ID

TVIS10014913

Fusion event

HBV-C1orf229 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

301

Orient

+

Integrated sequence

CAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTC| |TTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCAT

Chromosome

chr1

Cytoband

q44

Reference genome

Start

End

247279175/247115873 (Hg38)

Orient

-

Location type

Promoter

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-6789-3p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-744-5p ; hsa-mir-3648 ; hsa-mir-146b-3p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-134-3p ; hsa-mir-6775-5p ; hsa-mir-5090

Nearest miRNA

hsa-mir-101-1/Upstream/3769618; hsa-mir-3124/Downstream/86094;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/3418, chr1-CpG: 17/Downstream/29

Upstream sequence

GAGGGCAGCTCAGAGCTCTGGGAAGTGCCTCTTCCCAGCATCTGTCCACACTGTGCTCACCAGTGCCTTGGCGTCATCCCCTGAGAGGTGGGCATATGTC

Downstream sequence

CCTGTGGGCGGGTGACAGCAAGGTCATCACGGGGAGGGGGCGTGTCCCTGTGGGCGGGTGACAGCAAGGTCATCACGGGGAGGGGGCGTGTCCCTGTGGG