Basic Information
VIS ID
TVIS10014914
Fusion event
HBV-SNHG31 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
260
Orient
-
Integrated sequence
AGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTG| |GTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACT
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
215692960/214828236 (Hg38)
End
215692960/214828236 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNHG31
Nearest miRNA
hsa-mir-10b/Upstream/1070077; hsa-mir-1244-1/Downstream/3072277;
Nearest TSS
ENST00000437798/Upstream/18007; ENST00000420134/Downstream/132156;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/17908, chr2-CpG: 62/Downstream/483590
Upstream sequence
GGAGTGTAACATTGCAAAACAATGTtttttaattttttattattattattattttttaagacagagtctcactctgtcgcccaggctggaatgcagtggg
Downstream sequence
gtgatcttggctcactgcaacctctacctccagggtttaagaaattatctgcctcagcctcccgaatagctgggactacaggcgcccgccaccatgccca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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