VISDB Viral Integration Site DataBase

VIS ID

TVIS10014916

Fusion event

HBV-TRIML2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

219

Orient

-

Integrated sequence

GTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTG| |TTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGT

Chromosome

chr4

Cytoband

q35.2

Reference genome

Start

End

189028263/188107109 (Hg38)

Orient

+

Location type

Promoter

Target gene

miRNAs that regulate target gene

hsa-mir-5096 ; hsa-mir-1273e ; hsa-mir-203a-3p ; hsa-mir-636 ; hsa-mir-1909-5p ; hsa-mir-520f-3p ; hsa-mir-302c-3p

Nearest miRNA

hsa-mir-12113/Upstream/3168669;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/230, chr4-CpG: 33/Downstream/52585

Upstream sequence

TGGAAACTGAAATAAAGTATGTACTGGAACAGAACCTAAGAATATAATCATACTAATACAGTAATATGCTTAATATAATTATTGTGCAAAACACAGGGAG

Downstream sequence

gttcaaccgactctcctgcctcagcctcccgagtagctgggactacaggcgcgtgaaaccacacccagctaattttttgtatttttagtagagacggggt