VISDB Viral Integration Site DataBase

VIS ID

TVIS10014933

Fusion event

HBV-KLF13 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2714

Orient

+

Integrated sequence

GAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAAC| |ATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTG

Chromosome

chr15

Cytoband

q13.3

Reference genome

Start

End

31629964/31337761 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-372-3p ; hsa-mir-302d-3p ; hsa-mir-125b-5p ; hsa-mir-31-5p ; hsa-mir-125a-5p ; hsa-mir-98-5p ; hsa-mir-335-5p ; hsa-mir-1200 ; hsa-mir-1257 ; hsa-mir-3163 ; hsa-mir-4324 ; hsa-mir-4329 ; hsa-mir-3662 ; hsa-mir-4452 ; hsa-mir-4524a-3p ; hsa-mir-892c-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-7113-5p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-490-3p ; hsa-mir-613 ; hsa-mir-619-3p ; hsa-mir-6128 ; hsa-mir-8066 ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-766-5p ; hsa-mir-7515 ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-9500 ; hsa-mir-7851-3p ; hsa-mir-7106-5p ; hsa-mir-1289 ; hsa-mir-765 ; hsa-mir-4722-5p ; hsa-mir-6124 ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6165 ; hsa-mir-6867-5p ; hsa-mir-6793-3p ; hsa-mir-378a-5p ; hsa-mir-630 ; hsa-mir-544b ; hsa-mir-506-5p ; hsa-mir-4435 ; hsa-mir-4663 ; hsa-mir-3194-5p ; hsa-mir-3670 ; hsa-mir-3190-5p ; hsa-mir-6858-3p ; hsa-mir-4438 ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-556-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-2117 ; hsa-mir-6504-3p ; hsa-mir-148a-5p ; hsa-mir-6726-3p ; hsa-mir-4467 ; hsa-mir-566 ; hsa-mir-668-5p ; hsa-mir-18b-3p ; hsa-mir-6087 ; hsa-mir-4509 ; hsa-mir-1249-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-4755-5p ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-6501-3p ; hsa-mir-3614-3p ; hsa-mir-193a-5p ; hsa-mir-4251 ; hsa-mir-539-5p ; hsa-mir-541-3p ; hsa-mir-548az-5p ; hsa-mir-548t-5p ; hsa-mir-654-5p ; hsa-mir-6761-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-92a-2-5p ; hsa-mir-1207-5p ; hsa-mir-2392 ; hsa-mir-4446-3p ; hsa-mir-4656 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-6132 ; hsa-mir-6836-5p ; hsa-mir-6869-5p ; hsa-mir-7150 ; hsa-mir-8077

Nearest miRNA

hsa-mir-1268a/Upstream/272620; hsa-mir-10393/Downstream/3044308;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/8071, chr15-CpG: 36/Downstream/34294

Upstream sequence

tcctgaatactgtaggcaactgtaacacaatggtaagcattttgtatctaaatatagaaaaaggtacaattaaaatggggtgtcgtcttatgggaccagc

Downstream sequence

ctctcgtcccacgtggactgtcattgtttgaaacgtcattatgtggtgcatgactgTACTTTGCTGCTTGGCCTAAGGTGCCAGGGCATTCTCTGGGTAA