VISDB Viral Integration Site DataBase

VIS ID

TVIS10014934

Fusion event

HBV-MRPS15 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

845

Orient

-

Integrated sequence

TGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAAC| |AAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAAT

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

36927592/36461991 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-4279 ; hsa-mir-6868-3p ; hsa-mir-6881-3p ; hsa-mir-6515-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-877-3p ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-10a-3p ; hsa-mir-7152-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-6818-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-5088-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-4695-5p

Nearest miRNA

hsa-mir-12136/Upstream/1792297; hsa-mir-101-1/Downstream/699572;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/11268, chr1-CpG: 63/Downstream/1822

Upstream sequence

AAGTAGCCGAGCTCCATGAGTGCCATCTGCCTTGCTGACCACCCACCCTCACCACACCTGGACACCTGGGCCCCTGCCTCCTTCTAGATCAAGCTTCAGC

Downstream sequence

TACAGCAAGCCAAGTCTCAAAGCCACTGTCTTTCCCCACTCCCCGACAATCCTCCCAGGGCCCCCTGCCTCCTCTACTAGGTTTCTTCCTGCTTACTTCT