Basic Information
VIS ID
TVIS10014935
Fusion event
HBV-chr11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
2006
Orient
+
Integrated sequence
ACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTC| |AGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTA
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
122687039/122816331 (Hg38)
End
122687039/122816331 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/664023; hsa-mir-3167/Downstream/565109;
Nearest TSS
ENST00000527297/Upstream/21553; ENST00000533416/Downstream/22169;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/159560, chr11-CpG: 51/Downstream/66347
Nearby gene
UBASH3B(No orient, 1851)
Upstream sequence
ttcgggtatagtgccctgaactccATGTCACCTTCATGGTTTACTACTACCCACCATCTACCTCAAGGAGTTGCACCAAGAATGATCCAGAGAGTGAGAA
Downstream sequence
TTTGGGTAAGAGAGAGGGCACATTCAGCTCAAACTAGAATCTGCACTTCTAAAAGCCATAGACCATTTTTTGTTGTTGTTGTTGtttttatgtttttgtt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate